On MR, mural T2 signal is the most intuitive discriminator: a thickened wall that is bright on fat-saturated T2 (edema) favors active inflammation; a thickened wall that is dark on T2 favors fibrosis. Intramural fat (T1 bright, non-fat-sat) indicates chronic remodeling and is unrelated to whether active inflammation is present.
| Feature | Active inflammation | Chronic / fibrotic |
|---|---|---|
| Mural T2 signal | High (edema) | Low despite thickening |
| DWI | Restricted (high b, low ADC) | Unrestricted — not used to call fibrosis |
| Enhancement | Avid mucosal-predominant, or transmural | Delayed / progressive gain |
| Cine / motility | Narrowing transient (peristalsis preserved) | Fixed narrowing, loss of peristalsis |
| Ulceration | Present (marker of severe activity) | Absent (healed) |
| Mural fat | — | Present (submucosal fat) |
| Mesentery | Comb sign, fat stranding/edema, reactive nodes | Fibrofatty proliferation (creeping fat) |
| Stricture + upstream dilation | May be inflammatory | Characteristic of fibrostenotic disease |
| Pseudopolyps | — | Reparative / post-inflammatory (quiescent) |
Subtypes follow the four-category scheme (active inflammatory, fistulizing/perforating, fibrostenotic, reparative/regenerative), with a mixed category when active and fibrotic signs coexist — as they do in most strictures.
The SAR consensus notes a stratified/layered enhancement pattern can be produced by submucosal edema, intramural fat, or inflammation — so on its own it does not separate active from chronic disease. The tool therefore reports enhancement by avidity and distribution (mucosal-predominant vs. transmural) and leans on T2 signal, DWI, ulceration, and mesenteric signs to make the call, rather than layering.
A stricture is luminal narrowing with unequivocal upstream dilation. SAR 2018 used a >3 cm upstream-caliber cut; the 2025 SAR update lowered the pre-stenotic dilation threshold to ≥2.5 cm. The tool flags dilation at ≥2.5 cm and notes the caliber. Most Crohn's strictures contain both inflammation and fibrosis — when active signs coexist with a stricture, the segment is called mixed.
CT cannot assess intramural edema, mural T2 signal, DWI, or mural fat the way MR does, so those inputs are hidden in CT mode and the wording shifts to attenuation/enhancement. Enhancement, wall thickening, ulceration, stricture, penetrating disease, comb sign, and fibrofatty proliferation remain assessable.
The optional readout is the simplified MaRIA (Ordás et al., Gastroenterology 2019): one point each for wall thickening >3 mm, mural edema, perienteric fat stranding, and ulcers. >1 = active; ≥2 = severe. It is gadolinium-free and validated against endoscopy, but is a research/trial index rather than routine dictation, so it is kept out of the copied Findings by default. MaRIA/sMaRIA require MR (the edema term needs T2) and so are not offered in CT mode.
Guglielmo FF, Bruining DH, et al. Small Bowel Crohn Disease at CT and MR Enterography — SAR consensus reporting recommendations, Radiology 2018. Somwaru AS, Levy AD, et al. MR Enterography of IBD with Endoscopic Correlation (four-subtype table), RadioGraphics 2017. Leyendecker JR, et al. MR Enterography of Crohn Disease — technique and subtype imaging (Clermont/London indices, cine differentiation). Sinha R, et al. MR Enterography of Crohn Disease (imaging-based subtypes), AJR. Timpone VM, et al. pictorial essay, AJR. Ordás I, et al. simplified MaRIA, Gastroenterology 2019. Rimola J, et al. MaRIA validation, Inflamm Bowel Dis 2011. Dane B, et al. SAR consensus on defining strictures, Radiology 2025.
Interpret findings with endoscopy, histology and the clinical picture.