Based on the Memorial Sloan Kettering Cancer Center watch-and-wait MRI regression schema (as provided). Interpret with multidisciplinary review.
| Assessment | Complete response | Near-complete response | Incomplete response |
|---|---|---|---|
| Endoscopy (clinical ref.) |
Flat white scar; telangiectasia; no ulcer; no nodularity | Irregular mucosa; small mucosal nodules or minor abnormality; superficial ulceration; mild persisting erythema of the scar | Visible tumor |
| Digital rectal exam (clinical ref.) |
Normal | Smooth induration or minor mucosal abnormalities | Palpable tumor nodules |
| MRI — T2W | Only dark T2 signal, no intermediate T2 signal AND no visible lymph nodes | Mostly dark T2 signal, some remaining intermediate signal AND/OR partial regression of lymph nodes | More intermediate than dark T2 signal, no T2 scar AND/OR no regression of lymph nodes |
| MRI — DWI | No visible tumor on B800–B1000 AND/OR lack of low signal on ADC map (uniform linear wall signal above tumor is OK) | Significant regression of signal on B800–B1000 AND/OR minimal or low residual signal on ADC map | Insignificant regression of signal on B800–B1000 AND/OR obvious low signal on ADC map |